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VSTM2A suppresses colorectal cancer and antagonizes Wnt signaling receptor LRP6

Hyperactivation of Wnt/β-catenin signaling pathway is a critical step in colorectal tumorigenesis. In this study, we identified that V-set and transmembrane domain containing 2A (VSTM2A) was a top-downregulated secreted protein that negatively regulated Wnt singling pathways in colorectal cancer (CR...

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Detalles Bibliográficos
Autores principales:	Dong, Yujuan, Zhang, Yanquan, Kang, Wei, Wang, Guoping, Chen, Huarong, Higashimori, Akira, Nakatsu, Geicho, Go, Minnie, Tong, Joanna HM, Zheng, Shu, To, Ka Fai, Sung, Joseph JY, Yang, Xiaoyong, Ng, Simon SM, Yu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771244/ https://www.ncbi.nlm.nih.gov/pubmed/31588233 http://dx.doi.org/10.7150/thno.34989

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