Molecular basis for GIGYF–Me31B complex assembly in 4EHP-mediated translational repression

GIGYF (Grb10-interacting GYF [glycine–tyrosine–phenylalanine domain]) proteins coordinate with 4EHP (eIF4E [eukaryotic initiation factor 4E] homologous protein), the DEAD (Asp–Glu–Ala–Asp)-box helicase Me31B/DDX6, and mRNA-binding proteins to elicit transcript-specific repression. However, the under...

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Detalles Bibliográficos
Autores principales: Peter, Daniel, Ruscica, Vincenzo, Bawankar, Praveen, Weber, Ramona, Helms, Sigrun, Valkov, Eugene, Igreja, Cátia, Izaurralde, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771390/
https://www.ncbi.nlm.nih.gov/pubmed/31439631
http://dx.doi.org/10.1101/gad.329219.119

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