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Sequence determinants of polyadenylation-mediated regulation

The cleavage and polyadenylation reaction is a crucial step in transcription termination and pre-mRNA maturation in human cells. Despite extensive research, the encoding of polyadenylation-mediated regulation of gene expression within the DNA sequence is not well understood. Here, we utilized a mass...

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Detalles Bibliográficos
Autores principales:	Vainberg Slutskin, Ilya, Weinberger, Adina, Segal, Eran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771402/ https://www.ncbi.nlm.nih.gov/pubmed/31530582 http://dx.doi.org/10.1101/gr.247312.118

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