LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly

Dysregulated endogenous retroelements (EREs) are increasingly implicated in the initiation, progression, and immune surveillance of human cancer. However, incomplete knowledge of ERE activity limits mechanistic studies. By using pan-cancer de novo transcript assembly, we uncover the extent and compl...

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Detalles Bibliográficos
Autores principales: Attig, Jan, Young, George R., Hosie, Louise, Perkins, David, Encheva-Yokoya, Vesela, Stoye, Jonathan P., Snijders, Ambrosius P., Ternette, Nicola, Kassiotis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771403/
https://www.ncbi.nlm.nih.gov/pubmed/31537638
http://dx.doi.org/10.1101/gr.248922.119

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