Transcriptional alterations in glioma result primarily from DNA methylation–independent mechanisms

In cancer cells, aberrant DNA methylation is commonly associated with transcriptional alterations, including silencing of tumor suppressor genes. However, multiple epigenetic mechanisms, including polycomb repressive marks, contribute to gene deregulation in cancer. To dissect the relative contribut...

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Detalles Bibliográficos
Autores principales: Court, Franck, Le Boiteux, Elisa, Fogli, Anne, Müller-Barthélémy, Mélanie, Vaurs-Barrière, Catherine, Chautard, Emmanuel, Pereira, Bruno, Biau, Julian, Kemeny, Jean-Louis, Khalil, Toufic, Karayan-Tapon, Lucie, Verrelle, Pierre, Arnaud, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771409/
https://www.ncbi.nlm.nih.gov/pubmed/31533980
http://dx.doi.org/10.1101/gr.249219.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771409/
https://www.ncbi.nlm.nih.gov/pubmed/31533980
http://dx.doi.org/10.1101/gr.249219.119

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