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A simulation study on the effect of optimized high permittivity materials on fetal imaging at 3T
PURPOSE: One of the main concerns in fetal MRI is the radiofrequency power that is absorbed both by the mother and the fetus. Passive shimming using high permittivity materials in the form of “dielectric pads” has previously been shown to increase the [Formula: see text] efficiency and homogeneity i...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771485/ https://www.ncbi.nlm.nih.gov/pubmed/31199014 http://dx.doi.org/10.1002/mrm.27849 |
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author | van Gemert, Jeroen Brink, Wyger Remis, Rob Webb, Andrew |
author_facet | van Gemert, Jeroen Brink, Wyger Remis, Rob Webb, Andrew |
author_sort | van Gemert, Jeroen |
collection | PubMed |
description | PURPOSE: One of the main concerns in fetal MRI is the radiofrequency power that is absorbed both by the mother and the fetus. Passive shimming using high permittivity materials in the form of “dielectric pads” has previously been shown to increase the [Formula: see text] efficiency and homogeneity in different applications, while reducing the specific absorption rate (SAR). In this work, we study the effect of optimized dielectric pads for 3 pregnant models. METHODS: Pregnant models in the 3rd, 7th, and 9th months of gestation were used for simulations in a birdcage coil at 3T. Dielectric pads were optimized regions of interest (ROI) using previously developed methods for [Formula: see text] efficiency and homogeneity and were designed for 2 ROIs: the entire fetus and the brain of the fetus. The SAR was evaluated in terms of the whole‐body SAR, average SAR in the fetus and amniotic fluid, and maximum 10 g‐averaged SAR in the mother, fetus, and amniotic fluid. RESULTS: The optimized dielectric pads increased the transmit efficiency up to 55% and increased the [Formula: see text] homogeneity in almost every tested configuration. The [Formula: see text] ‐normalized whole‐body SAR was reduced by more than 31% for all body models. The [Formula: see text] ‐normalized local SAR was reduced in most scenarios by up to 62%. CONCLUSION: Simulations have shown that optimized high permittivity pads can reduce SAR in pregnant subjects at the 3rd, 7th, and 9th month of gestation, while improving the transmit field homogeneity in the fetus. However, significantly more work is required to demonstrate that fetal imaging is safe under standard operating conditions. |
format | Online Article Text |
id | pubmed-6771485 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-67714852019-10-03 A simulation study on the effect of optimized high permittivity materials on fetal imaging at 3T van Gemert, Jeroen Brink, Wyger Remis, Rob Webb, Andrew Magn Reson Med Full Papers—Preclinical and Clinical Imaging PURPOSE: One of the main concerns in fetal MRI is the radiofrequency power that is absorbed both by the mother and the fetus. Passive shimming using high permittivity materials in the form of “dielectric pads” has previously been shown to increase the [Formula: see text] efficiency and homogeneity in different applications, while reducing the specific absorption rate (SAR). In this work, we study the effect of optimized dielectric pads for 3 pregnant models. METHODS: Pregnant models in the 3rd, 7th, and 9th months of gestation were used for simulations in a birdcage coil at 3T. Dielectric pads were optimized regions of interest (ROI) using previously developed methods for [Formula: see text] efficiency and homogeneity and were designed for 2 ROIs: the entire fetus and the brain of the fetus. The SAR was evaluated in terms of the whole‐body SAR, average SAR in the fetus and amniotic fluid, and maximum 10 g‐averaged SAR in the mother, fetus, and amniotic fluid. RESULTS: The optimized dielectric pads increased the transmit efficiency up to 55% and increased the [Formula: see text] homogeneity in almost every tested configuration. The [Formula: see text] ‐normalized whole‐body SAR was reduced by more than 31% for all body models. The [Formula: see text] ‐normalized local SAR was reduced in most scenarios by up to 62%. CONCLUSION: Simulations have shown that optimized high permittivity pads can reduce SAR in pregnant subjects at the 3rd, 7th, and 9th month of gestation, while improving the transmit field homogeneity in the fetus. However, significantly more work is required to demonstrate that fetal imaging is safe under standard operating conditions. John Wiley and Sons Inc. 2019-06-14 2019-11 /pmc/articles/PMC6771485/ /pubmed/31199014 http://dx.doi.org/10.1002/mrm.27849 Text en © 2019 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Full Papers—Preclinical and Clinical Imaging van Gemert, Jeroen Brink, Wyger Remis, Rob Webb, Andrew A simulation study on the effect of optimized high permittivity materials on fetal imaging at 3T |
title | A simulation study on the effect of optimized high permittivity materials on fetal imaging at 3T |
title_full | A simulation study on the effect of optimized high permittivity materials on fetal imaging at 3T |
title_fullStr | A simulation study on the effect of optimized high permittivity materials on fetal imaging at 3T |
title_full_unstemmed | A simulation study on the effect of optimized high permittivity materials on fetal imaging at 3T |
title_short | A simulation study on the effect of optimized high permittivity materials on fetal imaging at 3T |
title_sort | simulation study on the effect of optimized high permittivity materials on fetal imaging at 3t |
topic | Full Papers—Preclinical and Clinical Imaging |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771485/ https://www.ncbi.nlm.nih.gov/pubmed/31199014 http://dx.doi.org/10.1002/mrm.27849 |
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