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A tumor‐targeting nanomedicine carrying the p53 gene crosses the blood–brain barrier and enhances anti‐PD‐1 immunotherapy in mouse models of glioblastoma

Despite its anticipated clinical potential, anti‐PD‐1 immunotherapy has only yielded poor outcomes in recent clinical trials for glioblastoma patients. Strategies combining anti‐PD‐1 antibody with other treatment modalities are being explored to alter the immunosuppressive microenvironment that appe...

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Detalles Bibliográficos
Autores principales:	Kim, Sang‐Soo, Harford, Joe B., Moghe, Manish, Slaughter, Tiffani, Doherty, Caroline, Chang, Esther H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Tumor Immunology and Microenvironment
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771527/ https://www.ncbi.nlm.nih.gov/pubmed/31241175 http://dx.doi.org/10.1002/ijc.32531

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