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Randomized phase I clinical trial of anti–α‐synuclein antibody BIIB054
BACKGROUND: Pathological and genetic evidence implicates toxic effects of aggregated α‐synuclein in the pathophysiology of neuronal dysfunction and degeneration in Parkinson's disease. Immunotherapy targeting aggregated α‐synuclein is a promising strategy for delaying disease progression. OBJEC...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771554/ https://www.ncbi.nlm.nih.gov/pubmed/31211448 http://dx.doi.org/10.1002/mds.27738 |