Cargando…

Diverse Immunomodulatory Effects of Individual IFNα Subtypes on Virus-Specific CD8(+) T Cell Responses

Clinical administration of Interferon α (IFNα) resulted in limited therapeutic success against some viral infections. Immune modulation of CD8(+) T cell responses during IFNα therapy is believed to play a pivotal role in promoting viral clearance. However, these clinical studies primarily focused on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dickow, Julia, Francois, Sandra, Kaiserling, Rouven-Luca, Malyshkina, Anna, Drexler, Ingo, Westendorf, Astrid Maria, Lang, Karl Sebastian, Santiago, Mario L., Dittmer, Ulf, Sutter, Kathrin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771563/ https://www.ncbi.nlm.nih.gov/pubmed/31608062 http://dx.doi.org/10.3389/fimmu.2019.02255

Ejemplares similares

Induction of Type I Interferons by Therapeutic Nanoparticle-Based Vaccination Is Indispensable to Reinforce Cytotoxic CD8(+) T Cell Responses During Chronic Retroviral Infection
por: Knuschke, Torben, et al.
Publicado: (2018)

Immunotherapy With Interferon α11, But Not Interferon Beta, Controls Persistent Retroviral Infection
por: Schwerdtfeger, Mara, et al.
Publicado: (2022)

Different antiviral effects of IFNα subtypes in a mouse model of HBV infection
por: Song, Jingjiao, et al.
Publicado: (2017)

IFNα subtype-specific susceptibility of HBV in the course of chronic infection
por: Xie, Xiaohong, et al.
Publicado: (2022)

Qualitative Differences Between the IFNα subtypes and IFNβ Influence Chronic Mucosal HIV-1 Pathogenesis
por: Guo, Kejun, et al.
Publicado: (2020)

Different Biological Activities of Specific Interferon Alpha Subtypes
por: Hasenkrug, Kim J., et al.
Publicado: (2019)

Cytotoxic CD4(+) T cells in chronic viral infections and cancer
por: Malyshkina, Anna, et al.
Publicado: (2023)

Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection
por: Malyshkina, Anna, et al.
Publicado: (2017)

Distinct Type I Interferon Subtypes Differentially Stimulate T Cell Responses in HIV-1-Infected Individuals
por: Karakoese, Zehra, et al.
Publicado: (2022)

Interferon-alpha Subtype 11 Activates NK Cells and Enables Control of Retroviral Infection
por: Gibbert, Kathrin, et al.
Publicado: (2012)

Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities
por: Matos, Aline da Rocha, et al.
Publicado: (2019)

HIV infection does not alter interferon α/β receptor 2 expression on mucosal immune cells
por: Ickler, Julia, et al.
Publicado: (2020)

Interferon (IFN)-λ Takes the Helm: Immunomodulatory Roles of Type III IFNs
por: Zanoni, Ivan, et al.
Publicado: (2017)

The Cytotoxic Activity of Natural Killer Cells Is Suppressed by IL-10(+) Regulatory T Cells During Acute Retroviral Infection
por: Littwitz-Salomon, Elisabeth, et al.
Publicado: (2018)

Concurrent administration of IFNα14 and cART in TKO-BLT mice enhances suppression of HIV-1 viremia but does not eliminate the latent reservoir
por: Sutter, Kathrin, et al.
Publicado: (2019)

SRSF1 acts as an IFN-I-regulated cellular dependency factor decisively affecting HIV-1 post-integration steps
por: Sertznig, Helene, et al.
Publicado: (2022)

Insufficient natural killer cell responses against retroviruses: how to improve NK cell killing of retrovirus-infected cells
por: Littwitz-Salomon, Elisabeth, et al.
Publicado: (2016)

Exploring the immunomodulatory role of virtual memory CD8(+) T cells: Role of IFN gamma in tumor growth control
por: Savid-Frontera, Constanza, et al.
Publicado: (2022)

Mitochondrial CMPK2 mediates immunomodulatory and antiviral activities through IFN-dependent and IFN-independent pathways
por: Lai, Jenn-Haung, et al.
Publicado: (2021)

Immunotherapy-induced cytotoxic T follicular helper cells reduce numbers of retrovirus-infected reservoir cells in B cell follicles
por: Malyshkina, Anna, et al.
Publicado: (2023)

Immunomodulatory potential of anti-IFN-beta antibodies on monocyte-derived macrophages
por: Sominanda, Ajith, et al.
Publicado: (2023)

CD47 restricts antiviral function of alveolar macrophages during influenza virus infection
por: Wenzek, Christina, et al.
Publicado: (2022)

Modified vaccinia virus Ankara as antigen delivery system: how can we best use its potential?
por: Drexler, Ingo, et al.
Publicado: (2004)

Hypoxia-inducible factor 1α is Essential for Macrophage-mediated Erythroblast Proliferation in Acute Friend Retrovirus Infection
por: Schreiber, Timm, et al.
Publicado: (2017)

Immunoactivation induced by chronic viral infection inhibits viral replication and drives immunosuppression through sustained IFN‐I responses
por: Honke, Nadine, et al.
Publicado: (2015)

Diverse Anti-Tumor Immune Potential Driven by Individual IFNα Subtypes
por: Buzzai, Anthony C., et al.
Publicado: (2020)

Induction of Noxa-Mediated Apoptosis by Modified Vaccinia Virus Ankara Depends on Viral Recognition by Cytosolic Helicases, Leading to IRF-3/IFN-β-Dependent Induction of Pro-Apoptotic Noxa
por: Eitz Ferrer, Pedro, et al.
Publicado: (2011)

Immune suppression of vaccine-induced CD8(+) T-cell responses by gamma retrovirus envelope is mediated by interleukin-10-producing CD4(+) T cells
por: Podschwadt, Philip, et al.
Publicado: (2022)

CEACAM1 promotes CD8(+) T cell responses and improves control of a chronic viral infection
por: Khairnar, Vishal, et al.
Publicado: (2018)

Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity
por: Dittmer, Ulf, et al.
Publicado: (2019)

Superior antiviral activity of IFNβ in genital HSV-1 infection
por: Schmitz, Yasmin, et al.
Publicado: (2022)

Antiviral, Immunomodulatory and Antiproliferative Activities of Recombinant Soluble IFNAR2 without IFN-ß Mediation
por: Hurtado-Guerrero, Isaac, et al.
Publicado: (2020)

Differential levels of IFNα subtypes in autoimmunity and viral infection
por: Bondet, Vincent, et al.
Publicado: (2021)

Infection of B Cell Follicle-Resident Cells by Friend Retrovirus Occurs during Acute Infection and Is Maintained during Viral Persistence
por: Windmann, Sonja, et al.
Publicado: (2019)

CD38: An Immunomodulatory Molecule in Inflammation and Autoimmunity
por: Piedra-Quintero, Zayda L., et al.
Publicado: (2020)

TLR ligand induced IL-6 counter-regulates the anti-viral CD8(+) T cell response during an acute retrovirus infection
por: Wu, Weimin, et al.
Publicado: (2015)

Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells
por: Duhan, Vikas, et al.
Publicado: (2021)

A Combination of Anti-PD-L1 Treatment and Therapeutic Vaccination Facilitates Improved Retroviral Clearance via Reactivation of Highly Exhausted T Cells
por: Knuschke, Torben, et al.
Publicado: (2021)

PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8(+) T Cell Killing
por: Akhmetzyanova, Ilseyar, et al.
Publicado: (2015)

Correction: PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing
por: Akhmetzyanova, Ilseyar, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_q7vgck13cdp6l8m8eirbqt1biu