SCO‐792, an enteropeptidase inhibitor, improves disease status of diabetes and obesity in mice

AIMS: Enteropeptidase is a serine protease localized on the duodenal brush border that catalyzes the conversion of inactive trypsinogen into active trypsin, thereby regulating protein breakdown in the gut. We evaluated the effects of SCO‐792, a novel enteropeptidase inhibitor, in mice. MATERIALS AND...

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Detalles Bibliográficos
Autores principales: Yashiro, Hiroaki, Hamagami, Kenichi, Hiyoshi, Hideyuki, Sugama, Jun, Tsuchimori, Kazue, Yamaguchi, Fuminari, Moritoh, Yusuke, Sasaki, Minoru, Maekawa, Tsuyoshi, Yamada, Yukio, Watanabe, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771630/
https://www.ncbi.nlm.nih.gov/pubmed/31144422
http://dx.doi.org/10.1111/dom.13799

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