Cargando…

Astrocyte‐specific transcriptome analysis using the ALDH1L1 bacTRAP mouse reveals novel biomarkers of astrogliosis in response to neurotoxicity

Neurotoxicology is hampered by the inability to predict regional and cellular targets of toxicant‐induced damage. Evaluating astrogliosis overcomes this problem because reactive astrocytes highlight the location of toxicant‐induced damage. While enhanced expression of glial fibrillary acidic protein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Michalovicz, Lindsay T., Kelly, Kimberly A., Vashishtha, Saurabh, Ben‐Hamo, Rotem, Efroni, Sol, Miller, Julie V., Locker, Alicia R., Sullivan, Kimberly, Broderick, Gordon, Miller, Diane B., O’Callaghan, James P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771645/ https://www.ncbi.nlm.nih.gov/pubmed/31222732 http://dx.doi.org/10.1111/jnc.14800

Ejemplares similares

Early Activation of STAT3 Regulates Reactive Astrogliosis Induced by Diverse Forms of Neurotoxicity
por: O'Callaghan, James P., et al.
Publicado: (2014)

Corticosterone primes the neuroinflammatory response to Gulf War Illness‐relevant organophosphates independently of acetylcholinesterase inhibition
por: Locker, Alicia R., et al.
Publicado: (2017)

Gene expression and network-based analysis reveals a novel role for hsa-miR-9 and drug control over the p38 network in glioblastoma multiforme progression
por: Ben-Hamo, Rotem, et al.
Publicado: (2011)

Biomarker robustness reveals the PDGF network as driving disease outcome in ovarian cancer patients in multiple studies
por: Ben-Hamo, Rotem, et al.
Publicado: (2012)

The whole-organism heavy chain B cell repertoire from Zebrafish self-organizes into distinct network features
por: Ben-Hamo, Rotem, et al.
Publicado: (2011)

Correction: Gene expression and network-based analysis reveals a novel role for hsa-miR-9 and drug control over the p38 network in glioblastoma multiforme progression
por: Ben-Hamo, Rotem, et al.
Publicado: (2012)

MicroRNA-Gene Association As a Prognostic Biomarker in Cancer Exposes Disease Mechanisms
por: Ben-Hamo, Rotem, et al.
Publicado: (2013)

MicroRNA regulation of molecular pathways as a generic mechanism and as a core disease phenotype
por: Ben-Hamo, Rotem, et al.
Publicado: (2015)

The β-adrenergic receptor blocker and anti-inflammatory drug propranolol mitigates brain cytokine expression in a long-term model of Gulf War Illness
por: Michalovicz, Lindsay T., et al.
Publicado: (2021)

Corticosterone and exogenous glucose alter blood glucose levels, neurotoxicity, and vascular toxicity produced by methamphetamine
por: Bowyer, John F., et al.
Publicado: (2017)

Advancing the Role of Neuroimmunity and Genetic Susceptibility in Gulf War Illness
por: O'Callaghan, James P., et al.
Publicado: (2017)

hsa-miR-9 controls the mobility behavior of glioblastoma cells via regulation of MAPK14 signaling elements
por: Ben-Hamo, Rotem, et al.
Publicado: (2015)

Acetylcholinesterase inhibitor exposures as an initiating factor in the development of Gulf War Illness, a chronic neuroimmune disorder in deployed veterans
por: Michalovicz, Lindsay T., et al.
Publicado: (2020)

Supporting a Neuroimmune Basis of Gulf War Illness
por: O'Callaghan, James P., et al.
Publicado: (2016)

Prior exposure to corticosterone markedly enhances and prolongs the neuroinflammatory response to systemic challenge with LPS
por: Kelly, Kimberly A., et al.
Publicado: (2018)

SENP5 mediates breast cancer invasion via a TGFβRI SUMOylation cascade
por: Cashman, Rivki, et al.
Publicado: (2014)

Inducible targeting of CNS astrocytes in Aldh1l1-CreERT2 BAC transgenic mice
por: Winchenbach, Jan, et al.
Publicado: (2016)

Corticosterone and pyridostigmine/DEET exposure attenuate peripheral cytokine expression: Supporting a dominant role for neuroinflammation in a mouse model of Gulf War Illness
por: Michalovicz, Lindsay T., et al.
Publicado: (2018)

A Logic Model of Neuronal-Glial Interaction Suggests Altered Homeostatic Regulation in the Perpetuation of Neuroinflammation
por: Craddock, Travis J. A., et al.
Publicado: (2018)

Epigenetic impacts of stress priming of the neuroinflammatory response to sarin surrogate in mice: a model of Gulf War illness
por: Ashbrook, David G., et al.
Publicado: (2018)

A Projectile Concussive Impact Model Produces Neuroinflammation in Both Mild and Moderate-Severe Traumatic Brain Injury
por: Michalovicz, Lindsay T., et al.
Publicado: (2023)

Detecting Cancer Gene Networks Characterized by Recurrent Genomic Alterations in a Population
por: Efroni, Sol, et al.
Publicado: (2011)

Shift in GATA3 functions, and GATA3 mutations, control progression and clinical presentation in breast cancer
por: Cohen, Helit, et al.
Publicado: (2014)

Corticosterone primes the neuroinflammatory response to DFP in mice: potential animal model of Gulf War Illness
por: O'Callaghan, James P., et al.
Publicado: (2015)

Temporal Dynamics of Cerebral Blood Flow, Cortical Damage, Apoptosis, Astrocyte–Vasculature Interaction and Astrogliosis in the Pericontusional Region after Traumatic Brain Injury
por: Villapol, Sonia, et al.
Publicado: (2014)

Astrocyte elevated gene-1 regulates astrocyte responses to neural injury: implications for reactive astrogliosis and neurodegeneration
por: Vartak-Sharma, Neha, et al.
Publicado: (2012)

Blocking Formation of Neurotoxic Reactive Astrocytes is Beneficial Following Stroke
por: Prescott, Kimberly, et al.
Publicado: (2023)

Oligodendrocyte involvement in Gulf War Illness
por: Belgrad, Jillian, et al.
Publicado: (2019)

Activation of STAT3 Regulates Reactive Astrogliosis and Neuronal Death Induced by AβO Neurotoxicity
por: Toral-Rios, Danira, et al.
Publicado: (2020)

A pilot reverse virtual screening study suggests toxic exposures caused long-term epigenetic changes in Gulf War Illness
por: Jean-Pierre, Modeline, et al.
Publicado: (2022)

Reduction of astrogliosis and microgliosis by cerebrospinal fluid shunting in experimental hydrocephalus
por: Miller, Janet M, et al.
Publicado: (2007)

Transcriptomic analysis and 3D bioengineering of astrocytes indicate ROCK inhibition produces cytotrophic astrogliosis
por: O'Shea, Ross D., et al.
Publicado: (2015)

Predicting and affecting response to cancer therapy based on pathway-level biomarkers
por: Ben-Hamo, Rotem, et al.
Publicado: (2020)

Astrogenesis versus astrogliosis
por: Koob, Andrew O.
Publicado: (2017)

Reactive astrogliosis in response to hemorrhagic fever virus: microarray profile of Junin virus-infected human astrocytes
por: Kolokoltsova, Olga A, et al.
Publicado: (2014)

Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult rats
por: Fang, Ming, et al.
Publicado: (2015)

Systematic analysis of purified astrocytes after SCI unveils Zeb2os function during astrogliosis
por: Wei, Haichao, et al.
Publicado: (2021)

The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity
por: Lorenzo, Petra I., et al.
Publicado: (2021)

Astrocyte Dysfunctions and HIV-1 Neurotoxicity
por: Ton, Hoai, et al.
Publicado: (2013)

Role of astrocytes in manganese mediated neurotoxicity
por: Sidoryk-Wegrzynowicz, Marta, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_im6mthuahlm7qfib9poa8uclbe