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The combination of NPM1, DNMT3A, and IDH1/2 mutations leads to inferior overall survival in AML

Acute myeloid leukemia (AML) is a genetically heterogeneous disease with a clinical course predicted by recurrent cytogenetic abnormalities and/or gene mutations. The NPM1 insertion mutations define the largest distinct genetic subset, ∼30% of AML, and is considered a favorable risk marker if there...

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Detalles Bibliográficos
Autores principales:	Dunlap, Jennifer B., Leonard, Jessica, Rosenberg, Mara, Cook, Rachel, Press, Richard, Fan, Guang, Raess, Philipp W., Druker, Brian J., Traer, Elie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771683/ https://www.ncbi.nlm.nih.gov/pubmed/31145495 http://dx.doi.org/10.1002/ajh.25517

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