The combination of tamoxifen with amphotericin B, but not with fluconazole, has synergistic activity against the majority of clinical isolates of Cryptococcus neoformans

BACKGROUND: Cryptococcal meningitis has fatality rates of 40%‐70%, resulting in 200 000 deaths each year. The best outcomes are achieved with amphotericin combined with flucytosine but flucytosine is expensive and unavailable where most disease occurs. More effective and affordable treatments are ne...

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Detalles Bibliográficos
Autores principales: Hai, Trieu Phan, Van, Anh Duong, Ngan, Nguyen Thi Thuy, Nhat, Le Thanh Hoang, Lan, Nguyen Phu Huong, Vinh Chau, Nguyen V., Thwaites, Guy E., Krysan, Damian, Day, Jeremy N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771715/
https://www.ncbi.nlm.nih.gov/pubmed/31173410
http://dx.doi.org/10.1111/myc.12955

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