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High‐resolution analysis of the HLA‐A, ‐B, ‐C and ‐DRB1 alleles and national and regional haplotype frequencies based on 120 926 volunteers from the Italian Bone Marrow Donor Registry

HLA genes are highly polymorphic and structurally complex. They are located in the major histocompatibility complex (MHC) on chromosome 6, and the frequency of alleles and haplotypes varies widely among human populations. In this paper, we calculated the allele and haplotype frequencies using the HL...

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Detalles Bibliográficos
Autores principales: Sacchi, Nicoletta, Castagnetta, Mauro, Miotti, Valeria, Garbarino, Lucia, Gallina, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771744/
https://www.ncbi.nlm.nih.gov/pubmed/31207125
http://dx.doi.org/10.1111/tan.13613