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Study of chromatin remodeling genes implicates SMARCA4 as a putative player in oncogenesis in neuroblastoma

In neuroblastoma (NB), genetic alterations in chromatin remodeling (CRGs) and epigenetic modifier genes (EMGs) have been described. We sought to determine their frequency and clinical impact. Whole exome (WES)/whole genome sequencing (WGS) data and targeted sequencing (TSCA®) of exonic regions of 33...

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Detalles Bibliográficos
Autores principales: Bellini, Angela, Bessoltane‐Bentahar, Nadia, Bhalshankar, Jaydutt, Clement, Nathalie, Raynal, Virginie, Baulande, Sylvain, Bernard, Virginie, Danzon, Adrien, Chicard, Mathieu, Colmet‐Daage, Léo, Pierron, Gaelle, Le Roux, Laura, Planchon, Julien M., Combaret, Valérie, Lapouble, Eve, Corradini, Nadège, Thebaud, Estelle, Gambart, Marion, Valteau‐Couanet, Dominique, Michon, Jean, Louis‐Brennetot, Caroline, Janoueix‐Lerosey, Isabelle, Defachelles, Anne‐Sophie, Bourdeaut, Franck, Delattre, Olivier, Schleiermacher, Gudrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771805/
https://www.ncbi.nlm.nih.gov/pubmed/31018240
http://dx.doi.org/10.1002/ijc.32361