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Mechanisms and biomedical implications of –1 programmed ribosome frameshifting on viral and bacterial mRNAs

Some proteins are expressed as a result of a ribosome frameshifting event that is facilitated by a slippery site and downstream secondary structure elements in the mRNA. This review summarizes recent progress in understanding mechanisms of –1 frameshifting in several viral genes, including IBV 1a/1b...

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Detalles Bibliográficos
Autores principales: Korniy, Natalia, Samatova, Ekaterina, Anokhina, Maria M., Peske, Frank, Rodnina, Marina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771820/
https://www.ncbi.nlm.nih.gov/pubmed/31222875
http://dx.doi.org/10.1002/1873-3468.13478