Topology and enzymatic properties of a canonical Polycomb repressive complex 1 isoform

Polycomb repressive complex 1 (PRC1) catalyses monoubiquitination of histone H2A on Lys119, promoting gene silencing. Cells at different developmental stages and in different tissues express different PRC1 isoforms. The topology, subunit composition, structural architecture and molecular mechanism o...

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Detalles Bibliográficos
Autores principales: Colombo, Matteo, Pessey, Ombeline, Marcia, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771824/
https://www.ncbi.nlm.nih.gov/pubmed/31093962
http://dx.doi.org/10.1002/1873-3468.13442

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