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A new insight into purinergic pharmacology: Three fungal species as natural P2X7R antagonists

P2X7 is a purinergic receptor involved in important physiological functions and pathological processes, such as inflammation, neurodegeneration, and pain. Despite its relevance, there is no selective antagonist useful in the treatment of diseases related to this receptor. In this context, research f...

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Detalles Bibliográficos
Autores principales: Soares‐Bezerra, Rômulo José, da Silva Ferreira, Natiele Carla, de Almeida Alves, Tânia Maria, Zani, Carlos Leomar, Rosa, Luiz Henrique, Faria, Robson Xavier, da Silva Frutuoso, Válber, Alves, Luiz Anastacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771832/
https://www.ncbi.nlm.nih.gov/pubmed/31264271
http://dx.doi.org/10.1002/ptr.6412