Spatial and episodic memory tasks promote temporal lobe interictal spikes

Reflex epilepsies have been demonstrated to exploit specific networks that subserve normal physiological function. It is unclear whether more common forms of epilepsy share this particular feature. By measuring interictal spikes in patients with a range of epilepsies, we show that 2 tasks known to s...

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Autores principales: Vivekananda, Umesh, Bush, Daniel, Bisby, James A., Diehl, Beate, Jha, Ashwani, Nachev, Parashkev, Rodionov, Roman, Burgess, Neil, Walker, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771851/
https://www.ncbi.nlm.nih.gov/pubmed/31177577
http://dx.doi.org/10.1002/ana.25519
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author Vivekananda, Umesh
Bush, Daniel
Bisby, James A.
Diehl, Beate
Jha, Ashwani
Nachev, Parashkev
Rodionov, Roman
Burgess, Neil
Walker, Matthew C.
author_facet Vivekananda, Umesh
Bush, Daniel
Bisby, James A.
Diehl, Beate
Jha, Ashwani
Nachev, Parashkev
Rodionov, Roman
Burgess, Neil
Walker, Matthew C.
author_sort Vivekananda, Umesh
collection PubMed
description Reflex epilepsies have been demonstrated to exploit specific networks that subserve normal physiological function. It is unclear whether more common forms of epilepsy share this particular feature. By measuring interictal spikes in patients with a range of epilepsies, we show that 2 tasks known to specifically engage the hippocampus and temporal neocortex promoted increased interictal spiking within these regions, whereas a nonhippocampal dependent task did not. This indicates that interictal spike frequency may reflect the processing demands being placed on specific functional–anatomical networks in epilepsy. ANN NEUROL 2019;86:304–309
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spelling pubmed-67718512019-10-07 Spatial and episodic memory tasks promote temporal lobe interictal spikes Vivekananda, Umesh Bush, Daniel Bisby, James A. Diehl, Beate Jha, Ashwani Nachev, Parashkev Rodionov, Roman Burgess, Neil Walker, Matthew C. Ann Neurol Brief Communications Reflex epilepsies have been demonstrated to exploit specific networks that subserve normal physiological function. It is unclear whether more common forms of epilepsy share this particular feature. By measuring interictal spikes in patients with a range of epilepsies, we show that 2 tasks known to specifically engage the hippocampus and temporal neocortex promoted increased interictal spiking within these regions, whereas a nonhippocampal dependent task did not. This indicates that interictal spike frequency may reflect the processing demands being placed on specific functional–anatomical networks in epilepsy. ANN NEUROL 2019;86:304–309 John Wiley & Sons, Inc. 2019-06-20 2019-08 /pmc/articles/PMC6771851/ /pubmed/31177577 http://dx.doi.org/10.1002/ana.25519 Text en © 2019 The Authors. Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communications
Vivekananda, Umesh
Bush, Daniel
Bisby, James A.
Diehl, Beate
Jha, Ashwani
Nachev, Parashkev
Rodionov, Roman
Burgess, Neil
Walker, Matthew C.
Spatial and episodic memory tasks promote temporal lobe interictal spikes
title Spatial and episodic memory tasks promote temporal lobe interictal spikes
title_full Spatial and episodic memory tasks promote temporal lobe interictal spikes
title_fullStr Spatial and episodic memory tasks promote temporal lobe interictal spikes
title_full_unstemmed Spatial and episodic memory tasks promote temporal lobe interictal spikes
title_short Spatial and episodic memory tasks promote temporal lobe interictal spikes
title_sort spatial and episodic memory tasks promote temporal lobe interictal spikes
topic Brief Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771851/
https://www.ncbi.nlm.nih.gov/pubmed/31177577
http://dx.doi.org/10.1002/ana.25519
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