Genetic risk for alzheimer disease is distinct from genetic risk for amyloid deposition

OBJECTIVE: Alzheimer disease (AD) is the most common form of dementia and is responsible for a huge and growing health care burden in the developed and developing world. The polygenic risk score (PRS) approach has shown 75 to 84% prediction accuracy of identifying individuals with AD risk. METHODS:...

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Detalles Bibliográficos
Autores principales: Leonenko, Ganna, Shoai, Maryam, Bellou, Eftychia, Sims, Rebecca, Williams, Julie, Hardy, John, Escott‐Price, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771864/
https://www.ncbi.nlm.nih.gov/pubmed/31199530
http://dx.doi.org/10.1002/ana.25530

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