The STAT3 inhibitor galiellalactone inhibits the generation of MDSC‐like monocytes by prostate cancer cells and decreases immunosuppressive and tumorigenic factors

BACKGROUND: The transcription factor signal transducer and activator of transcription 3 (STAT3) is implicated in cancer drug resistance, metastasis, and immunosuppression and has been identified as a promising therapeutic target for new anticancer drugs. Myeloid‐derived suppressor cells (MDSCs) play...

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Detalles Bibliográficos
Autores principales: Hellsten, Rebecka, Lilljebjörn, Lisa, Johansson, Martin, Leandersson, Karin, Bjartell, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771992/
https://www.ncbi.nlm.nih.gov/pubmed/31348843
http://dx.doi.org/10.1002/pros.23885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771992/
https://www.ncbi.nlm.nih.gov/pubmed/31348843
http://dx.doi.org/10.1002/pros.23885

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