Major drug resistance mutations to HIV-1 protease inhibitors (PI) among patients exposed to PI class failing antiretroviral therapy in São Paulo State, Brazil

BACKGROUND: Protease inhibitors (PI) are especially important in salvage therapy. Previous treatment failure with a PI containing regimen may elicit resistance mutations, reducing PI susceptibility and limiting treatment options. The aim of this study was to describe major PI mutations among patient...

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Detalles Bibliográficos
Autores principales: Soldi, Giselle de Faria Romero, Ribeiro, Isadora Coutinho, Ahagon, Cintia Mayumi, Coelho, Luana Portes Ozório, Cabral, Gabriela Bastos, Lopes, Giselle Ibette Silva López, Ferreira, João Leandro de Paula, Brígido, Luís Fernando de Macedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772045/
https://www.ncbi.nlm.nih.gov/pubmed/31574109
http://dx.doi.org/10.1371/journal.pone.0223210

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