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Dosage regulation, and variation in gene expression and copy number of human Y chromosome ampliconic genes
The Y chromosome harbors nine multi-copy ampliconic gene families expressed exclusively in testis. The gene copies within each family are >99% identical to each other, which poses a major challenge in evaluating their copy number. Recent studies demonstrated high variation in Y ampliconic gene co...
Autores principales: | Vegesna, Rahulsimham, Tomaszkiewicz, Marta, Medvedev, Paul, Makova, Kateryna D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772104/ https://www.ncbi.nlm.nih.gov/pubmed/31525193 http://dx.doi.org/10.1371/journal.pgen.1008369 |
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