Deoxygenative Borylation of Secondary and Tertiary Alcohols

Two different approaches for the deoxygenative radical borylation of secondary and tertiary alcohols are presented. These transformations either proceed through a metal‐free silyl‐radical‐mediated pathway or utilize visible‐light photoredox catalysis. Readily available xanthates or methyl oxalates a...

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Detalles Bibliográficos
Autores principales: Friese, Florian W., Studer, Armido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772128/
https://www.ncbi.nlm.nih.gov/pubmed/31050141
http://dx.doi.org/10.1002/anie.201904028
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author Friese, Florian W.
Studer, Armido
author_facet Friese, Florian W.
Studer, Armido
author_sort Friese, Florian W.
collection PubMed
description Two different approaches for the deoxygenative radical borylation of secondary and tertiary alcohols are presented. These transformations either proceed through a metal‐free silyl‐radical‐mediated pathway or utilize visible‐light photoredox catalysis. Readily available xanthates or methyl oxalates are used as radical precursors. The reactions show broad substrate scope and high functional‐group tolerance, and are conducted under mild and practical conditions.
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spelling pubmed-67721282019-10-07 Deoxygenative Borylation of Secondary and Tertiary Alcohols Friese, Florian W. Studer, Armido Angew Chem Int Ed Engl Communications Two different approaches for the deoxygenative radical borylation of secondary and tertiary alcohols are presented. These transformations either proceed through a metal‐free silyl‐radical‐mediated pathway or utilize visible‐light photoredox catalysis. Readily available xanthates or methyl oxalates are used as radical precursors. The reactions show broad substrate scope and high functional‐group tolerance, and are conducted under mild and practical conditions. John Wiley and Sons Inc. 2019-06-05 2019-07-08 /pmc/articles/PMC6772128/ /pubmed/31050141 http://dx.doi.org/10.1002/anie.201904028 Text en © 2019 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Communications
Friese, Florian W.
Studer, Armido
Deoxygenative Borylation of Secondary and Tertiary Alcohols
title Deoxygenative Borylation of Secondary and Tertiary Alcohols
title_full Deoxygenative Borylation of Secondary and Tertiary Alcohols
title_fullStr Deoxygenative Borylation of Secondary and Tertiary Alcohols
title_full_unstemmed Deoxygenative Borylation of Secondary and Tertiary Alcohols
title_short Deoxygenative Borylation of Secondary and Tertiary Alcohols
title_sort deoxygenative borylation of secondary and tertiary alcohols
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772128/
https://www.ncbi.nlm.nih.gov/pubmed/31050141
http://dx.doi.org/10.1002/anie.201904028
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