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Divergent memory responses driven by adenoviral vectors are impacted by epitope competition

Adenoviral vectors induce robust epitope‐specific CD8(+) T cell responses. Within the repertoire of responses generated both conventional memory evolution and the phenomenon of memory inflation are seen. The rules governing which epitopes inflate are not fully known, but may include a role for both...

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Detalles Bibliográficos
Autores principales: Colston, Julia M, Hutchings, Claire, Chinnakannan, Senthil, Highton, Andrew, Perez‐Shibayama, Christian, Ludewig, Burkhard, Klenerman, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772135/
https://www.ncbi.nlm.nih.gov/pubmed/31106398
http://dx.doi.org/10.1002/eji.201948143

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