Cargando…
Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation
OBJECTIVE: The aim of this study was to evaluate the cerebral outcomes of patients underwent novel triple‐branched stent graft implantation combined with the intraoperative monitoring of regional cerebral oxygen saturation. METHODS: One hundred thirty‐seven consecutive patients who underwent the sur...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772148/ https://www.ncbi.nlm.nih.gov/pubmed/31269292 http://dx.doi.org/10.1111/jocs.14130 |
_version_ | 1783455847445168128 |
---|---|
author | Lin, Yong Chen, Mei‐Fang Chen, Liang‐Wan Wang, Jie‐Bo Zhang, Hui Li, Ruo‐Meng |
author_facet | Lin, Yong Chen, Mei‐Fang Chen, Liang‐Wan Wang, Jie‐Bo Zhang, Hui Li, Ruo‐Meng |
author_sort | Lin, Yong |
collection | PubMed |
description | OBJECTIVE: The aim of this study was to evaluate the cerebral outcomes of patients underwent novel triple‐branched stent graft implantation combined with the intraoperative monitoring of regional cerebral oxygen saturation. METHODS: One hundred thirty‐seven consecutive patients who underwent the surgery of triple‐branched stent graft implantation in our department were enrolled in this retrospective case‐control study. The patients in group A received brain protection based on the intraoperative monitoring of regional cerebral oxygen saturation and the patients in group B received conventional brain protection. The general clinical data, the types of corrective surgeries, the intraoperative situations, the postoperative complications, and the midterm outcomes of the patients were analyzed. RESULTS: The incidence of postoperative cerebral dysfunction in the patients of group A was significantly lower than that in the patients in group B (3.2% vs 14.9%, P = .020). We found significant differences in the incubation times (30.3 ± 22.1 vs 42.3 ± 27.9 hours, P = .014), the lengths of intensive care unit stay (58.0 ± 54.3 vs 79.7 ± 55.5 hours, P = .004), and the hospital stays (19.3 ± 6.7 vs 24.9 ± 17.3 days, P = .045). A descending trend in the mortality rates was observed between the patients in the two groups based on the 20 months of observation; however, this trend was not statistically significant (1.6% vs 6.8%, P = .218). CONCLUSIONS: The novel triple‐branched stent graft implantation procedure combined with intraoperative monitoring of the regional cerebral oxygen saturation was an effective treatment for Stanford type A aortic dissection, with a relatively low incidence of postoperative cerebral dysfunction. |
format | Online Article Text |
id | pubmed-6772148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-67721482019-10-07 Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation Lin, Yong Chen, Mei‐Fang Chen, Liang‐Wan Wang, Jie‐Bo Zhang, Hui Li, Ruo‐Meng J Card Surg Original Articles OBJECTIVE: The aim of this study was to evaluate the cerebral outcomes of patients underwent novel triple‐branched stent graft implantation combined with the intraoperative monitoring of regional cerebral oxygen saturation. METHODS: One hundred thirty‐seven consecutive patients who underwent the surgery of triple‐branched stent graft implantation in our department were enrolled in this retrospective case‐control study. The patients in group A received brain protection based on the intraoperative monitoring of regional cerebral oxygen saturation and the patients in group B received conventional brain protection. The general clinical data, the types of corrective surgeries, the intraoperative situations, the postoperative complications, and the midterm outcomes of the patients were analyzed. RESULTS: The incidence of postoperative cerebral dysfunction in the patients of group A was significantly lower than that in the patients in group B (3.2% vs 14.9%, P = .020). We found significant differences in the incubation times (30.3 ± 22.1 vs 42.3 ± 27.9 hours, P = .014), the lengths of intensive care unit stay (58.0 ± 54.3 vs 79.7 ± 55.5 hours, P = .004), and the hospital stays (19.3 ± 6.7 vs 24.9 ± 17.3 days, P = .045). A descending trend in the mortality rates was observed between the patients in the two groups based on the 20 months of observation; however, this trend was not statistically significant (1.6% vs 6.8%, P = .218). CONCLUSIONS: The novel triple‐branched stent graft implantation procedure combined with intraoperative monitoring of the regional cerebral oxygen saturation was an effective treatment for Stanford type A aortic dissection, with a relatively low incidence of postoperative cerebral dysfunction. John Wiley and Sons Inc. 2019-07-03 2019-09 /pmc/articles/PMC6772148/ /pubmed/31269292 http://dx.doi.org/10.1111/jocs.14130 Text en © 2019 The Authors. Journal of Cardiac Surgery Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Lin, Yong Chen, Mei‐Fang Chen, Liang‐Wan Wang, Jie‐Bo Zhang, Hui Li, Ruo‐Meng Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation |
title | Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation |
title_full | Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation |
title_fullStr | Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation |
title_full_unstemmed | Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation |
title_short | Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation |
title_sort | midterm cerebral outcomes of stanford type a aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772148/ https://www.ncbi.nlm.nih.gov/pubmed/31269292 http://dx.doi.org/10.1111/jocs.14130 |
work_keys_str_mv | AT linyong midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation AT chenmeifang midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation AT chenliangwan midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation AT wangjiebo midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation AT zhanghui midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation AT liruomeng midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation |