Cargando…

Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation

OBJECTIVE: The aim of this study was to evaluate the cerebral outcomes of patients underwent novel triple‐branched stent graft implantation combined with the intraoperative monitoring of regional cerebral oxygen saturation. METHODS: One hundred thirty‐seven consecutive patients who underwent the sur...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Yong, Chen, Mei‐Fang, Chen, Liang‐Wan, Wang, Jie‐Bo, Zhang, Hui, Li, Ruo‐Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772148/
https://www.ncbi.nlm.nih.gov/pubmed/31269292
http://dx.doi.org/10.1111/jocs.14130
_version_ 1783455847445168128
author Lin, Yong
Chen, Mei‐Fang
Chen, Liang‐Wan
Wang, Jie‐Bo
Zhang, Hui
Li, Ruo‐Meng
author_facet Lin, Yong
Chen, Mei‐Fang
Chen, Liang‐Wan
Wang, Jie‐Bo
Zhang, Hui
Li, Ruo‐Meng
author_sort Lin, Yong
collection PubMed
description OBJECTIVE: The aim of this study was to evaluate the cerebral outcomes of patients underwent novel triple‐branched stent graft implantation combined with the intraoperative monitoring of regional cerebral oxygen saturation. METHODS: One hundred thirty‐seven consecutive patients who underwent the surgery of triple‐branched stent graft implantation in our department were enrolled in this retrospective case‐control study. The patients in group A received brain protection based on the intraoperative monitoring of regional cerebral oxygen saturation and the patients in group B received conventional brain protection. The general clinical data, the types of corrective surgeries, the intraoperative situations, the postoperative complications, and the midterm outcomes of the patients were analyzed. RESULTS: The incidence of postoperative cerebral dysfunction in the patients of group A was significantly lower than that in the patients in group B (3.2% vs 14.9%, P = .020). We found significant differences in the incubation times (30.3 ± 22.1 vs 42.3 ± 27.9 hours, P = .014), the lengths of intensive care unit stay (58.0 ± 54.3 vs 79.7 ± 55.5 hours, P = .004), and the hospital stays (19.3 ± 6.7 vs 24.9 ± 17.3 days, P = .045). A descending trend in the mortality rates was observed between the patients in the two groups based on the 20 months of observation; however, this trend was not statistically significant (1.6% vs 6.8%, P = .218). CONCLUSIONS: The novel triple‐branched stent graft implantation procedure combined with intraoperative monitoring of the regional cerebral oxygen saturation was an effective treatment for Stanford type A aortic dissection, with a relatively low incidence of postoperative cerebral dysfunction.
format Online
Article
Text
id pubmed-6772148
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-67721482019-10-07 Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation Lin, Yong Chen, Mei‐Fang Chen, Liang‐Wan Wang, Jie‐Bo Zhang, Hui Li, Ruo‐Meng J Card Surg Original Articles OBJECTIVE: The aim of this study was to evaluate the cerebral outcomes of patients underwent novel triple‐branched stent graft implantation combined with the intraoperative monitoring of regional cerebral oxygen saturation. METHODS: One hundred thirty‐seven consecutive patients who underwent the surgery of triple‐branched stent graft implantation in our department were enrolled in this retrospective case‐control study. The patients in group A received brain protection based on the intraoperative monitoring of regional cerebral oxygen saturation and the patients in group B received conventional brain protection. The general clinical data, the types of corrective surgeries, the intraoperative situations, the postoperative complications, and the midterm outcomes of the patients were analyzed. RESULTS: The incidence of postoperative cerebral dysfunction in the patients of group A was significantly lower than that in the patients in group B (3.2% vs 14.9%, P = .020). We found significant differences in the incubation times (30.3 ± 22.1 vs 42.3 ± 27.9 hours, P = .014), the lengths of intensive care unit stay (58.0 ± 54.3 vs 79.7 ± 55.5 hours, P = .004), and the hospital stays (19.3 ± 6.7 vs 24.9 ± 17.3 days, P = .045). A descending trend in the mortality rates was observed between the patients in the two groups based on the 20 months of observation; however, this trend was not statistically significant (1.6% vs 6.8%, P = .218). CONCLUSIONS: The novel triple‐branched stent graft implantation procedure combined with intraoperative monitoring of the regional cerebral oxygen saturation was an effective treatment for Stanford type A aortic dissection, with a relatively low incidence of postoperative cerebral dysfunction. John Wiley and Sons Inc. 2019-07-03 2019-09 /pmc/articles/PMC6772148/ /pubmed/31269292 http://dx.doi.org/10.1111/jocs.14130 Text en © 2019 The Authors. Journal of Cardiac Surgery Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Lin, Yong
Chen, Mei‐Fang
Chen, Liang‐Wan
Wang, Jie‐Bo
Zhang, Hui
Li, Ruo‐Meng
Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation
title Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation
title_full Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation
title_fullStr Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation
title_full_unstemmed Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation
title_short Midterm cerebral outcomes of Stanford type A aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation
title_sort midterm cerebral outcomes of stanford type a aortic dissection in patients who underwent novel triple‐branched stent graft implantation combined with intraoperative monitoring of regional cerebral oxygen saturation
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772148/
https://www.ncbi.nlm.nih.gov/pubmed/31269292
http://dx.doi.org/10.1111/jocs.14130
work_keys_str_mv AT linyong midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation
AT chenmeifang midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation
AT chenliangwan midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation
AT wangjiebo midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation
AT zhanghui midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation
AT liruomeng midtermcerebraloutcomesofstanfordtypeaaorticdissectioninpatientswhounderwentnoveltriplebranchedstentgraftimplantationcombinedwithintraoperativemonitoringofregionalcerebraloxygensaturation