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Application techniques of a novel hemostat in cardiac operations: HEMOBLAST

BACKGROUND: Postoperative bleeding complications are associated with less favorable outcomes in cardiac surgery and contribute to excessive overall healthcare costs. HEMOBLAST (Biom'up, Lyon, France) (HB) is a novel ready‐to‐use hemostatic powder that consists of porcine collagen, bovine chondr...

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Autores principales: Bruckner, Brian A., Ngo, Uy, Ramchandani, Mahesh, Suarez, Erik, Awad, Samir, Reardon, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773212/
https://www.ncbi.nlm.nih.gov/pubmed/31348840
http://dx.doi.org/10.1111/jocs.14171
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author Bruckner, Brian A.
Ngo, Uy
Ramchandani, Mahesh
Suarez, Erik
Awad, Samir
Reardon, Michael
author_facet Bruckner, Brian A.
Ngo, Uy
Ramchandani, Mahesh
Suarez, Erik
Awad, Samir
Reardon, Michael
author_sort Bruckner, Brian A.
collection PubMed
description BACKGROUND: Postoperative bleeding complications are associated with less favorable outcomes in cardiac surgery and contribute to excessive overall healthcare costs. HEMOBLAST (Biom'up, Lyon, France) (HB) is a novel ready‐to‐use hemostatic powder that consists of porcine collagen, bovine chondroitin sulfate, and human pooled plasma thrombin that may help reduce surgical bleeding. AIMS: The aim of this study was to describe the techniques of application for this new combination powder‐based hemostat, HB, and demonstrate its use employing photographs of application methods during cardiac procedures. MATERIALS AND METHODS: The initial 24 procedures in which HB was used at our institution included: left ventricular assist device (LVAD) insertions, lung transplants, heart transplants, aortic valve replacements, coronary artery bypass grafting, and mitral valve repair. RESULTS: Hemostasis was achieved in all cases and there were no instances of mediastinitis, sternal infections, allergic reactions, or 30‐day mortality. DISCUSSION: This report describes the best methods of application of HB including use for treatment of mediastinal bleeding in a re‐operative procedure in a patient on antiplatelet agents and sternal bleeding during an LVAD insertion. Proper application can facilitate excellent hemostasis using this powder. CONCLUSION: HB is a novel powder‐based multiple component hemostatic agent that promotes focal or large area hemostasis. We have presented the techniques of use that are important to the successful application of HB to facilitate hemostasis.
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spelling pubmed-67732122019-10-07 Application techniques of a novel hemostat in cardiac operations: HEMOBLAST Bruckner, Brian A. Ngo, Uy Ramchandani, Mahesh Suarez, Erik Awad, Samir Reardon, Michael J Card Surg Surgical Technique BACKGROUND: Postoperative bleeding complications are associated with less favorable outcomes in cardiac surgery and contribute to excessive overall healthcare costs. HEMOBLAST (Biom'up, Lyon, France) (HB) is a novel ready‐to‐use hemostatic powder that consists of porcine collagen, bovine chondroitin sulfate, and human pooled plasma thrombin that may help reduce surgical bleeding. AIMS: The aim of this study was to describe the techniques of application for this new combination powder‐based hemostat, HB, and demonstrate its use employing photographs of application methods during cardiac procedures. MATERIALS AND METHODS: The initial 24 procedures in which HB was used at our institution included: left ventricular assist device (LVAD) insertions, lung transplants, heart transplants, aortic valve replacements, coronary artery bypass grafting, and mitral valve repair. RESULTS: Hemostasis was achieved in all cases and there were no instances of mediastinitis, sternal infections, allergic reactions, or 30‐day mortality. DISCUSSION: This report describes the best methods of application of HB including use for treatment of mediastinal bleeding in a re‐operative procedure in a patient on antiplatelet agents and sternal bleeding during an LVAD insertion. Proper application can facilitate excellent hemostasis using this powder. CONCLUSION: HB is a novel powder‐based multiple component hemostatic agent that promotes focal or large area hemostasis. We have presented the techniques of use that are important to the successful application of HB to facilitate hemostasis. John Wiley and Sons Inc. 2019-07-26 2019-09 /pmc/articles/PMC6773212/ /pubmed/31348840 http://dx.doi.org/10.1111/jocs.14171 Text en © 2019 The Authors. Journal of Cardiac Surgery Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/3.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Surgical Technique
Bruckner, Brian A.
Ngo, Uy
Ramchandani, Mahesh
Suarez, Erik
Awad, Samir
Reardon, Michael
Application techniques of a novel hemostat in cardiac operations: HEMOBLAST
title Application techniques of a novel hemostat in cardiac operations: HEMOBLAST
title_full Application techniques of a novel hemostat in cardiac operations: HEMOBLAST
title_fullStr Application techniques of a novel hemostat in cardiac operations: HEMOBLAST
title_full_unstemmed Application techniques of a novel hemostat in cardiac operations: HEMOBLAST
title_short Application techniques of a novel hemostat in cardiac operations: HEMOBLAST
title_sort application techniques of a novel hemostat in cardiac operations: hemoblast
topic Surgical Technique
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773212/
https://www.ncbi.nlm.nih.gov/pubmed/31348840
http://dx.doi.org/10.1111/jocs.14171
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