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Landscape of B cell immunity and related immune evasion in human cancers

Tumor-infiltrating B cells are an important component in the microenvironment with unclear anti-tumor impacts. We enhanced our previous computational algorithm TRUST to extract the B cell immunoglobulin (Ig) hypervariable regions from bulk tumor RNA-seq data. TRUST assembled over 30 million compleme...

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Detalles Bibliográficos
Autores principales:	Hu, Xihao, Zhang, Jian, Wang, Jin, Fu, Jingxin, Li, Taiwen, Zheng, Xiaoqi, Wang, Binbin, Gu, Shengqing, Jiang, Peng, Fan, Jingyu, Ying, Xiaomin, Zhang, Jing, Carroll, Michael C., Wucherpfennig, Kai W., Hacohen, Nir, Zhang, Fan, Zhang, Peng, Liu, Jun S., Li, Bo, Liu, X. Shirley
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773274/ https://www.ncbi.nlm.nih.gov/pubmed/30742113 http://dx.doi.org/10.1038/s41588-018-0339-x

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