Cargando…
Multibatch TMT Reveals False Positives, Batch Effects and Missing Values
Multiplexing strategies for large-scale proteomic analyses have become increasingly prevalent, tandem mass tags (TMT) in particular. Here we used a large iPSC proteomic experiment with twenty-four 10-plex TMT batches to evaluate the effect of integrating multiple TMT batches within a single analysis...
Autores principales: | Brenes, Alejandro, Hukelmann, Jens, Bensaddek, Dalila, Lamond, Angus I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773557/ https://www.ncbi.nlm.nih.gov/pubmed/31332098 http://dx.doi.org/10.1074/mcp.RA119.001472 |
Ejemplares similares
-
Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome
por: Brenes, Alejandro J., et al.
Publicado: (2021) -
Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development
por: Offenburger, Sarah-Lena, et al.
Publicado: (2017) -
Unlocking the chromatin code by deciphering protein–DNA interactions
por: Bensaddek, Dalila, et al.
Publicado: (2016) -
Micro‐proteomics with iterative data analysis: Proteome analysis in C. elegans at the single worm level
por: Bensaddek, Dalila, et al.
Publicado: (2016) -
Evaluating the use of HILIC in large-scale, multi dimensional proteomics: Horses for courses?
por: Bensaddek, Dalila, et al.
Publicado: (2015)