Total serum protein reference value as a clinical diagnostic index of equine proliferative enteropathy

Equine proliferative enteropathy (EPE) caused by Lawsonia intracellularis is characterized by hypoproteinemia. There are currently no reliable reports that provide a reference value for the total serum protein (TP) concentration to clinically diagnose EPE. The objective of this study was to statisti...

Descripción completa

Detalles Bibliográficos
Autores principales: UENO, Yasushi, UEMURA, Ryoko, NIWA, Hidekazu, HIGUCHI, Toru, SEKIGUCHI, Satoshi, SASAKI, Yosuke, SUEYOSHI, Masuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Equine Science 2019
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773620/
https://www.ncbi.nlm.nih.gov/pubmed/31592224
http://dx.doi.org/10.1294/jes.30.63
Descripción
Sumario:Equine proliferative enteropathy (EPE) caused by Lawsonia intracellularis is characterized by hypoproteinemia. There are currently no reliable reports that provide a reference value for the total serum protein (TP) concentration to clinically diagnose EPE. The objective of this study was to statistically determine the reference value. Feces and sera of 99 foals with EPE-like clinical signs and of 35 healthy foals were obtained. The samples were used for specific-gene detection of L. intracellularis, TP measurement, and specific-antibody detection against L. intracellularis. Based on these results, the optimal reference value for the TP concentration as a clinical diagnostic index of EPE was found to be ≤ 4.8 g/dl. This clinical diagnostic index will provide an effective approach for diagnosing EPE.

Ejemplares similares