The ubiquitin-like modifier FAT10 interferes with SUMO activation

The covalent attachment of the cytokine-inducible ubiquitin-like modifier HLA-F adjacent transcript 10 (FAT10) to hundreds of substrate proteins leads to their rapid degradation by the 26 S proteasome independently of ubiquitylation. Here, we identify another function of FAT10, showing that it inter...

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Detalles Bibliográficos
Autores principales: Aichem, Annette, Sailer, Carolin, Ryu, Stella, Catone, Nicola, Stankovic-Valentin, Nicolas, Schmidtke, Gunter, Melchior, Frauke, Stengel, Florian, Groettrup, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773726/
https://www.ncbi.nlm.nih.gov/pubmed/31575873
http://dx.doi.org/10.1038/s41467-019-12430-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773726/
https://www.ncbi.nlm.nih.gov/pubmed/31575873
http://dx.doi.org/10.1038/s41467-019-12430-z

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