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The ubiquitin-like modifier FAT10 interferes with SUMO activation
The covalent attachment of the cytokine-inducible ubiquitin-like modifier HLA-F adjacent transcript 10 (FAT10) to hundreds of substrate proteins leads to their rapid degradation by the 26 S proteasome independently of ubiquitylation. Here, we identify another function of FAT10, showing that it inter...
Autores principales: | Aichem, Annette, Sailer, Carolin, Ryu, Stella, Catone, Nicola, Stankovic-Valentin, Nicolas, Schmidtke, Gunter, Melchior, Frauke, Stengel, Florian, Groettrup, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773726/ https://www.ncbi.nlm.nih.gov/pubmed/31575873 http://dx.doi.org/10.1038/s41467-019-12430-z |
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