CD98hc (SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression

CD98 heavy chain (CD98hc) forms heteromeric amino acid (AA) transporters by interacting with different light chains. Cancer cells overexpress CD98hc-transporters in order to meet their increased nutritional and antioxidant demands, since they provide branched-chain AA (BCAA) and aromatic AA (AAA) av...

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Detalles Bibliográficos
Autores principales: Cano-Crespo, Sara, Chillarón, Josep, Junza, Alexandra, Fernández-Miranda, Gonzalo, García, Judit, Polte, Christine, R. de la Ballina, Laura, Ignatova, Zoya, Yanes, Óscar, Zorzano, Antonio, Stephan-Otto Attolini, Camille, Palacín, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773781/
https://www.ncbi.nlm.nih.gov/pubmed/31575908
http://dx.doi.org/10.1038/s41598-019-50547-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773781/
https://www.ncbi.nlm.nih.gov/pubmed/31575908
http://dx.doi.org/10.1038/s41598-019-50547-9

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