Cargando…
CD98hc (SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression
CD98 heavy chain (CD98hc) forms heteromeric amino acid (AA) transporters by interacting with different light chains. Cancer cells overexpress CD98hc-transporters in order to meet their increased nutritional and antioxidant demands, since they provide branched-chain AA (BCAA) and aromatic AA (AAA) av...
Autores principales: | Cano-Crespo, Sara, Chillarón, Josep, Junza, Alexandra, Fernández-Miranda, Gonzalo, García, Judit, Polte, Christine, R. de la Ballina, Laura, Ignatova, Zoya, Yanes, Óscar, Zorzano, Antonio, Stephan-Otto Attolini, Camille, Palacín, Manuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773781/ https://www.ncbi.nlm.nih.gov/pubmed/31575908 http://dx.doi.org/10.1038/s41598-019-50547-9 |
Ejemplares similares
-
Dependence of proliferative vascular smooth muscle cells on CD98hc (4F2hc, SLC3A2)
por: Fogelstrand, Per, et al.
Publicado: (2009) -
CD98hc (SLC3A2) regulation of skin homeostasis wanes with age
por: Boulter, Etienne, et al.
Publicado: (2013) -
CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling
por: Féral, Chloé C., et al.
Publicado: (2007) -
CD98hc (SLC3A2) drives integrin-dependent renal cancer cell behavior
por: Poettler, Marina, et al.
Publicado: (2013) -
LAT1 (SLC7A5) and CD98hc (SLC3A2) complex dynamics revealed by single-particle cryo-EM
por: Chiduza, George N., et al.
Publicado: (2019)