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Body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index

INTRODUCTION: An increased body mass index (BMI) (>25 kg/m(2)) is associated with a wide range of electrocardiographic changes. However, the association between electrocardiographic changes and BMI in healthy young individuals with a normal BMI (18.5–25 kg/m(2)) is unknown. The aim of this study...

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Autores principales: Hassing, G. J., van der Wall, H. E. C., van Westen, G. J. P., Kemme, M. J. B., Adiyaman, A., Elvan, A., Burggraaf, J., Gal, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bohn Stafleu van Loghum 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773792/
https://www.ncbi.nlm.nih.gov/pubmed/31111455
http://dx.doi.org/10.1007/s12471-019-1282-x
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author Hassing, G. J.
van der Wall, H. E. C.
van Westen, G. J. P.
Kemme, M. J. B.
Adiyaman, A.
Elvan, A.
Burggraaf, J.
Gal, P.
author_facet Hassing, G. J.
van der Wall, H. E. C.
van Westen, G. J. P.
Kemme, M. J. B.
Adiyaman, A.
Elvan, A.
Burggraaf, J.
Gal, P.
author_sort Hassing, G. J.
collection PubMed
description INTRODUCTION: An increased body mass index (BMI) (>25 kg/m(2)) is associated with a wide range of electrocardiographic changes. However, the association between electrocardiographic changes and BMI in healthy young individuals with a normal BMI (18.5–25 kg/m(2)) is unknown. The aim of this study was to evaluate the association between BMI and electrocardiographic parameters. METHODS: Data from 1,290 volunteers aged 18 to 30 years collected at our centre were analysed. Only subjects considered healthy by a physician after review of collected data with a normal BMI and in sinus rhythm were included in the analysis. Subjects with a normal BMI (18.5–25 kg/m(2)) were divided into BMI quartiles analysis and a backward multivariate regression analysis with a normal BMI as a continuous variable was performed. RESULTS: Mean age was 22.7 ± 3.0 years, mean BMI was 22.0, and 73.4% were male. There were significant differences between the BMI quartiles in terms of maximum P-wave duration, P-wave balance, total P-wave area in lead V1, PR-interval duration, and heart axis. In the multivariate model maximum P-wave duration (standardised coefficient (SC) = +0.112, P < 0.001), P-wave balance in lead V1 (SC = +0.072, P < 0.001), heart axis (SC = −0.164, P < 0.001), and Sokolow-Lyon voltage (SC = −0.097, P < 0.001) were independently associated with BMI. CONCLUSION: Increased BMI was related with discrete electrocardiographic alterations including an increased P-wave duration, increased P-wave balance, a leftward shift of the heart axis, and decreased Sokolow-Lyon voltage on a standard twelve lead electrocardiogram in healthy young individuals with a normal BMI.
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spelling pubmed-67737922019-10-17 Body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index Hassing, G. J. van der Wall, H. E. C. van Westen, G. J. P. Kemme, M. J. B. Adiyaman, A. Elvan, A. Burggraaf, J. Gal, P. Neth Heart J Original Article INTRODUCTION: An increased body mass index (BMI) (>25 kg/m(2)) is associated with a wide range of electrocardiographic changes. However, the association between electrocardiographic changes and BMI in healthy young individuals with a normal BMI (18.5–25 kg/m(2)) is unknown. The aim of this study was to evaluate the association between BMI and electrocardiographic parameters. METHODS: Data from 1,290 volunteers aged 18 to 30 years collected at our centre were analysed. Only subjects considered healthy by a physician after review of collected data with a normal BMI and in sinus rhythm were included in the analysis. Subjects with a normal BMI (18.5–25 kg/m(2)) were divided into BMI quartiles analysis and a backward multivariate regression analysis with a normal BMI as a continuous variable was performed. RESULTS: Mean age was 22.7 ± 3.0 years, mean BMI was 22.0, and 73.4% were male. There were significant differences between the BMI quartiles in terms of maximum P-wave duration, P-wave balance, total P-wave area in lead V1, PR-interval duration, and heart axis. In the multivariate model maximum P-wave duration (standardised coefficient (SC) = +0.112, P < 0.001), P-wave balance in lead V1 (SC = +0.072, P < 0.001), heart axis (SC = −0.164, P < 0.001), and Sokolow-Lyon voltage (SC = −0.097, P < 0.001) were independently associated with BMI. CONCLUSION: Increased BMI was related with discrete electrocardiographic alterations including an increased P-wave duration, increased P-wave balance, a leftward shift of the heart axis, and decreased Sokolow-Lyon voltage on a standard twelve lead electrocardiogram in healthy young individuals with a normal BMI. Bohn Stafleu van Loghum 2019-05-20 2019-10 /pmc/articles/PMC6773792/ /pubmed/31111455 http://dx.doi.org/10.1007/s12471-019-1282-x Text en © The Author(s) 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Hassing, G. J.
van der Wall, H. E. C.
van Westen, G. J. P.
Kemme, M. J. B.
Adiyaman, A.
Elvan, A.
Burggraaf, J.
Gal, P.
Body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index
title Body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index
title_full Body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index
title_fullStr Body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index
title_full_unstemmed Body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index
title_short Body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index
title_sort body mass index related electrocardiographic findings in healthy young individuals with a normal body mass index
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773792/
https://www.ncbi.nlm.nih.gov/pubmed/31111455
http://dx.doi.org/10.1007/s12471-019-1282-x
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