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Understanding the Origin and Diversity of Macrophages to Tailor Their Targeting in Solid Cancers
Tumor-associated macrophages (TAMs) are a major component of the tumor immune microenvironment (TIME) and are associated with a poor prognostic factor in several cancers. TAMs promote tumor growth by facilitating immunosuppression, angiogenesis, and inflammation, and can promote tumor recurrence pos...
Autores principales: | Kielbassa, Karoline, Vegna, Serena, Ramirez, Christel, Akkari, Leila |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773830/ https://www.ncbi.nlm.nih.gov/pubmed/31611871 http://dx.doi.org/10.3389/fimmu.2019.02215 |
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