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Balanced cholinergic modulation of spinal locomotor circuits via M2 and M3 muscarinic receptors

Neuromodulation ensures that neural circuits produce output that is flexible whilst remaining within an optimal operational range. The neuromodulator acetylcholine is released during locomotion to regulate spinal motor circuits. However, the range of receptors and downstream mechanisms by which acet...

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Detalles Bibliográficos
Autores principales: Nascimento, Filipe, Spindler, Lennart R. B., Miles, Gareth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773880/
https://www.ncbi.nlm.nih.gov/pubmed/31575899
http://dx.doi.org/10.1038/s41598-019-50452-1