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Two Simple Methods for Optimizing the Production of "Difficult-to-Express" GnRH-DFF40 Chimeric Protein

Purpose: GnRH-DFF40 (gonadotropin releasing hormone - DNA fragmentation factor 40) is a humanized recombinant immunotoxin and serves as a prospective candidate for targeted therapy of gonadotropin releasing hormone receptor (GnRHR) overexpressing malignancies. However, its production in Escherichia...

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Detalles Bibliográficos
Autores principales: Barazesh, Mahdi, Mostafavipour, Zohreh, Kavousipour, Soudabeh, Mohammadi, Shiva, Mokarram, Pooneh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773931/
https://www.ncbi.nlm.nih.gov/pubmed/31592077
http://dx.doi.org/10.15171/apb.2019.050

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