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Dihydropyrimidine Dehydrogenase Levels in Colorectal Cancer Cells Treated with a Combination of Heat Shock Protein 90 Inhibitor and Oxaliplatin or Capecitabine

Purpose: Dihydropyrimidine dehydrogenase (DPD) is the principal enzyme in the catabolism of fluoropyrimidine drugs including capecitabine. A recent report has suggested that oxaliplatin chemotherapy is associated with elevated DPD levels and chemoresistance pattern. As a newly developed chemotherape...

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Detalles Bibliográficos
Autores principales: Mohammadian, Mahshid, Zeynali-Moghaddam, Shima, Khadem Ansari, Mohammad Hassan, Rasmi, Yousef, Fathi Azarbayjani, Anahita, Kheradmand, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773945/
https://www.ncbi.nlm.nih.gov/pubmed/31592113
http://dx.doi.org/10.15171/apb.2019.052