Cargando…

A longitudinal assessment of retinal function and structure in the APP/PS1 transgenic mouse model of Alzheimer’s disease

BACKGROUND: A great body of evidence suggests that there are retinal functional and structural changes that occur in Alzheimer’s disease (AD). However, whether such changes are primary or secondary remains to be elucidated. We studied a range of retinal functional and structural parameters in associ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Georgevsky, Dana, Retsas, Stephanie, Raoufi, Newsha, Shimoni, Olga, Golzan, S. Mojtaba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774218/ https://www.ncbi.nlm.nih.gov/pubmed/31592131 http://dx.doi.org/10.1186/s40035-019-0170-z

Ejemplares similares

Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease
por: Hosseinpour Mashkani, Seyed Mostafa, et al.
Publicado: (2023)

Correlation of Retinal Nerve Fibre Layer Thickness and Spontaneous Retinal Venous Pulsations in Glaucoma and Normal Controls
por: Golzan, S. Mojtaba, et al.
Publicado: (2015)

RAGE and its ligand amyloid beta promote retinal ganglion cell loss following ischemia-reperfusion injury
por: Seyed Hosseini Fin, Nafiseh, et al.
Publicado: (2023)

Retinal vascular and structural changes are associated with amyloid burden in the elderly: ophthalmic biomarkers of preclinical Alzheimer’s disease
por: Golzan, S.Mojtaba, et al.
Publicado: (2017)

Longitudinal investigation of neuroinflammation and metabolite profiles in the APP (swe)×PS1(Δe9) transgenic mouse model of Alzheimer's disease
por: Chaney, Aisling, et al.
Publicado: (2017)

Humulus japonicus inhibits the progression of Alzheimer's disease in a APP/PS1 transgenic mouse model
por: Park, Tae-Shin, et al.
Publicado: (2017)

The effects of Gouqi extracts on Morris maze learning in the APP/PS1 double transgenic mouse model of Alzheimer’s disease
por: ZHANG, QIANLIN, et al.
Publicado: (2013)

Effects of triptolide on hippocampal microglial cells and astrocytes in the APP/PS1 double transgenic mouse model of Alzheimer's disease
por: Li, Jian-ming, et al.
Publicado: (2016)

Vaccine Development to Treat Alzheimer's Disease Neuropathology in APP/PS1 Transgenic Mice
por: Carrera, Iván, et al.
Publicado: (2012)

Examination of Longitudinal Alterations in Alzheimer’s Disease-Related Neurogenesis in an APP/PS1 Transgenic Mouse Model, and the Effects of P33, a Putative Neuroprotective Agent Thereon
por: Szögi, Titanilla, et al.
Publicado: (2022)

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice
por: Hiltunen, Mikko, et al.
Publicado: (2012)

Untargeted lipidomics reveals progression of early Alzheimer’s disease in APP/PS1 transgenic mice
por: Zhang, Xueju, et al.
Publicado: (2020)

Evodiamine derivatives improve cognitive abilities in APP(swe)/PS1(ΔE9) transgenic mouse models of Alzheimer's disease
por: Pang, Shuo, et al.
Publicado: (2020)

Cyclic Glycine-Proline Improves Memory and Reduces Amyloid Plaque Load in APP/PS1 Transgenic Mouse Model of Alzheimer's Disease
por: Arora, Tushar, et al.
Publicado: (2023)

Fecal microbiota transplantation alleviated Alzheimer’s disease-like pathogenesis in APP/PS1 transgenic mice
por: Sun, Jing, et al.
Publicado: (2019)

Ovocystatin Induced Changes in Expression of Alzheimer’s Disease Relevant Proteins in APP/PS1 Transgenic Mice
por: Stanczykiewicz, Bartlomiej, et al.
Publicado: (2022)

Abnormalities of plasma cytokines and spleen in senile APP/PS1/Tau transgenic mouse model
por: Yang, Seung-Hoon, et al.
Publicado: (2015)

The integration site of the APP transgene in the J20 mouse model of Alzheimer’s disease
por: Tosh, Justin L., et al.
Publicado: (2018)

Effects of (−)Epicatechin on the Pathology of APP/PS1 Transgenic Mice
por: Zeng, Yue-Qin, et al.
Publicado: (2014)

Author Correction: Untargeted lipidomics reveals progression of early Alzheimer’s disease in APP/PS1 transgenic mice
por: Zhang, Xueju, et al.
Publicado: (2021)

Neuropathological and behavioral features of an APP/PS1/MAPT (6xTg) transgenic model of Alzheimer’s disease
por: Tag, Sung Hyun, et al.
Publicado: (2022)

Cognitive Performance on the Montreal Cognitive Assessment Test and Retinal Structural and Functional Measures in Glaucoma
por: Bastani Viarsagh, Solmaz, et al.
Publicado: (2022)

Intranasal BMP9 Ameliorates Alzheimer Disease-Like Pathology and Cognitive Deficits in APP/PS1 Transgenic Mice
por: Wang, Zigao, et al.
Publicado: (2017)

Chronic caffeine treatment reverses memory impairment and the expression of brain BNDF and TrkB in the PS1/APP double transgenic mouse model of Alzheimer’s disease
por: HAN, KUN, et al.
Publicado: (2013)

DNA vaccines targeting amyloid-β oligomer ameliorate cognitive deficits of aged APP/PS1/tau triple-transgenic mouse models of Alzheimer’s disease
por: Sha, Sha, et al.
Publicado: (2022)

Comprehensive behavioral characterization of an APP/PS-1 double knock-in mouse model of Alzheimer's disease
por: Webster, Scott J, et al.
Publicado: (2013)

Milrinone Ameliorates the Neuroinflammation and Memory Function of Alzheimer’s Disease in an APP/PS1 Mouse Model
por: Chen, Qingyou, et al.
Publicado: (2021)

Neuroprotective effects of resistance physical exercise on the APP/PS1 mouse model of Alzheimer’s disease
por: Campos, Henrique Correia, et al.
Publicado: (2023)

Studies on APP metabolism related to age-associated mitochondrial dysfunction in APP/PS1 transgenic mice
por: Chen, Lizhi, et al.
Publicado: (2019)

Icariin Decreases the Expression of APP and BACE-1 and Reduces the β-amyloid Burden in an APP Transgenic Mouse Model of Alzheimer's Disease
por: Zhang, Lan, et al.
Publicado: (2014)

Data on COA-Cl administration to the APP/PS2 double-transgenic mouse model of Alzheimer׳s disease: Improved hippocampus-dependent learning and unchanged spontaneous physical activity
por: Kishimoto, Yasushi, et al.
Publicado: (2018)

Amelioration of Behavioral Impairments and Neuropathology by Antiepileptic Drug Topiramate in a Transgenic Alzheimer’s Disease Model Mice, APP/PS1
por: Owona, Brice Ayissi, et al.
Publicado: (2019)

Objective Quantification of Spontaneous Retinal Venous Pulsations Using a Novel Tablet-Based Ophthalmoscope
por: Shariflou, Sahar, et al.
Publicado: (2020)

Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice
por: Dickey, Chad A, et al.
Publicado: (2005)

Tanshinone IIA Alleviates the AD Phenotypes in APP and PS1 Transgenic Mice
por: Li, Fengling, et al.
Publicado: (2016)

The effects of treadmill exercise on autophagy in hippocampus of APP/PS1 transgenic mice
por: Zhao, Na, et al.
Publicado: (2018)

A Comparative Evaluation of a Novel Vaccine in APP/PS1 Mouse Models of Alzheimer's Disease
por: Carrera, Iván, et al.
Publicado: (2015)

An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model
por: Kempf, Stefan J., et al.
Publicado: (2016)

Active compounds of herbs ameliorate impaired cognition in APP/PS1 mouse model of Alzheimer’s disease
por: Yu, WenJun, et al.
Publicado: (2019)

The role of ADAM17 in cerebrovascular and cognitive function in the APP/PS1 mouse model of Alzheimer’s disease
por: Tian, Yanna, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_cma1o3tp36egrm08lui7jnd9mt