Bee venom phospholipase A2 ameliorates amyloidogenesis and neuroinflammation through inhibition of signal transducer and activator of transcription-3 pathway in Tg2576 mice

BACKGROUND: Neuroinflammation and accumulation of β-amyloid (Aβ) play a significant role in the onset and progression of Alzheimer’s disease (AD). Our previous study demonstrated that signal transducer and activator of transcription-3 (STAT3) plays a major role in neuroinflammation and amyloidogenes...

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Detalles Bibliográficos
Autores principales: Ham, Hyeon Joo, Han, Sang-Bae, Yun, Jaesuk, Yeo, In Jun, Ham, Young Wan, Kim, Se Hyun, Park, Pil-Hoon, Choi, Dong-Young, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774221/
https://www.ncbi.nlm.nih.gov/pubmed/31592103
http://dx.doi.org/10.1186/s40035-019-0167-7

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