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Cycloaddition Strategies for the Synthesis of Diverse Heterocyclic Spirocycles for Fragment‐Based Drug Discovery

In recent years the pharmaceutical industry has benefited from the advances made in fragment‐based drug discovery (FBDD) with more than 30 fragment‐derived drugs currently marketed or progressing through clinical trials. The success of fragment‐based drug discovery is entirely dependent upon the com...

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Detalles Bibliográficos
Autores principales: King, Thomas A., Stewart, Hannah L., Mortensen, Kim T., North, Andrew J. P., Sore, Hannah F., Spring, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774287/
https://www.ncbi.nlm.nih.gov/pubmed/31598091
http://dx.doi.org/10.1002/ejoc.201900847