Structure‐Based Design, Synthesis and Biological Evaluation of Bis‐Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase

The protozoan parasites Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp. are responsible for the severely debilitating neglected Tropical diseases of African sleeping sickness, Chagas disease and leishmaniasis, respectively. As part of our ongoing programme exploring the potential of simpli...

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Detalles Bibliográficos
Autores principales: Zacharova, Marija K., Tulloch, Lindsay B., Gould, Eoin R., Fraser, Andrew L., King, Elizabeth F., Menzies, Stefanie K., Smith, Terry K., Florence, Gordon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774295/
https://www.ncbi.nlm.nih.gov/pubmed/31598093
http://dx.doi.org/10.1002/ejoc.201900541

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