Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression

Glutamate (Glu)-mediated excitotoxicity is a major cause of amyotrophic lateral sclerosis (ALS) and our previous work highlighted that abnormal Glu release may represent a leading mechanism for excessive synaptic Glu. We demonstrated that group I metabotropic Glu receptors (mGluR1, mGluR5) produced...

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Detalles Bibliográficos
Autores principales: Bonifacino, Tiziana, Rebosio, Claudia, Provenzano, Francesca, Torazza, Carola, Balbi, Matilde, Milanese, Marco, Raiteri, Luca, Usai, Cesare, Fedele, Ernesto, Bonanno, Giambattista
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774337/
https://www.ncbi.nlm.nih.gov/pubmed/31540330
http://dx.doi.org/10.3390/ijms20184552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774337/
https://www.ncbi.nlm.nih.gov/pubmed/31540330
http://dx.doi.org/10.3390/ijms20184552

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