Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood

Neoantigen-specific T cells are increasingly viewed as important immunotherapy effectors, but physically isolating these rare cell populations is challenging. Here, we describe a sensitive method for the enumeration and isolation of neoantigen-specific CD8+ T cells from small samples of patient tumo...

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Detalles Bibliográficos
Autores principales: Peng, Songming, Zaretsky, Jesse M., Ng, Alphonsus H.C., Chour, William, Bethune, Michael T., Choi, Jongchan, Hsu, Alice, Holman, Elizabeth, Ding, Xiaozhe, Guo, Katherine, Kim, Jungwoo, Xu, Alexander M., Heath, John E., Noh, Won Jun, Zhou, Jing, Su, Yapeng, Lu, Yue, McLaughlin, Jami, Cheng, Donghui, Witte, Owen N., Baltimore, David, Ribas, Antoni, Heath, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774618/
https://www.ncbi.nlm.nih.gov/pubmed/31484081
http://dx.doi.org/10.1016/j.celrep.2019.07.106

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