Telomerase promotes formation of a telomere protective complex in cancer cells

Telomerase is a ribonucleoprotein complex that catalyzes addition of telomeric DNA repeats to maintain telomeres in replicating cells. Here, we demonstrate that the telomerase protein hTERT performs an additional role at telomeres that is independent of telomerase catalytic activity yet essential fo...

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Detalles Bibliográficos
Autores principales: Perera, Omesha N., Sobinoff, Alexander P., Teber, Erdahl T., Harman, Ashley, Maritz, Michelle F., Yang, Sile F., Pickett, Hilda A., Cesare, Anthony J., Arthur, Jonathan W., MacKenzie, Karen L., Bryan, Tracy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774720/
https://www.ncbi.nlm.nih.gov/pubmed/31616780
http://dx.doi.org/10.1126/sciadv.aav4409

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