4D functional ultrasound imaging of whole-brain activity in rodents

We developed a technology that extends the capabilities of functional ultrasound to whole-brain 4D neuroimaging. We implemented multiplane wave transmissions on matrix arrays at thousands of frames per second to provide volumetric recordings of cerebral blood volume changes at high spatiotemporal re...

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Detalles Bibliográficos
Autores principales: Rabut, Claire, Correia, Mafalda, Finel, Victor, Pezet, Sophie, Pernot, Mathieu, Deffieux, Thomas, Tanter, Mickael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774790/
https://www.ncbi.nlm.nih.gov/pubmed/31548704
http://dx.doi.org/10.1038/s41592-019-0572-y
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author Rabut, Claire
Correia, Mafalda
Finel, Victor
Pezet, Sophie
Pernot, Mathieu
Deffieux, Thomas
Tanter, Mickael
author_facet Rabut, Claire
Correia, Mafalda
Finel, Victor
Pezet, Sophie
Pernot, Mathieu
Deffieux, Thomas
Tanter, Mickael
author_sort Rabut, Claire
collection PubMed
description We developed a technology that extends the capabilities of functional ultrasound to whole-brain 4D neuroimaging. We implemented multiplane wave transmissions on matrix arrays at thousands of frames per second to provide volumetric recordings of cerebral blood volume changes at high spatiotemporal resolution. This approach is illustrated by several proofs-of-concept: real time multiple sensory stimuli, 4D functional connectivity and instantaneous tracking of epileptiform events within the whole brains of rodents.
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spelling pubmed-67747902020-03-23 4D functional ultrasound imaging of whole-brain activity in rodents Rabut, Claire Correia, Mafalda Finel, Victor Pezet, Sophie Pernot, Mathieu Deffieux, Thomas Tanter, Mickael Nat Methods Article We developed a technology that extends the capabilities of functional ultrasound to whole-brain 4D neuroimaging. We implemented multiplane wave transmissions on matrix arrays at thousands of frames per second to provide volumetric recordings of cerebral blood volume changes at high spatiotemporal resolution. This approach is illustrated by several proofs-of-concept: real time multiple sensory stimuli, 4D functional connectivity and instantaneous tracking of epileptiform events within the whole brains of rodents. 2019-09-23 2019-10 /pmc/articles/PMC6774790/ /pubmed/31548704 http://dx.doi.org/10.1038/s41592-019-0572-y Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Rabut, Claire
Correia, Mafalda
Finel, Victor
Pezet, Sophie
Pernot, Mathieu
Deffieux, Thomas
Tanter, Mickael
4D functional ultrasound imaging of whole-brain activity in rodents
title 4D functional ultrasound imaging of whole-brain activity in rodents
title_full 4D functional ultrasound imaging of whole-brain activity in rodents
title_fullStr 4D functional ultrasound imaging of whole-brain activity in rodents
title_full_unstemmed 4D functional ultrasound imaging of whole-brain activity in rodents
title_short 4D functional ultrasound imaging of whole-brain activity in rodents
title_sort 4d functional ultrasound imaging of whole-brain activity in rodents
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774790/
https://www.ncbi.nlm.nih.gov/pubmed/31548704
http://dx.doi.org/10.1038/s41592-019-0572-y
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