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Multiscale three-dimensional surface reconstruction and surface roughness of porcine left anterior descending coronary arteries
The aim of this study was to investigate the multiscale surface roughness characteristics of coronary arteries, to aid in the development of novel biomaterials and bioinspired medical devices. Porcine left anterior descending coronary arteries were dissected ex vivo, and specimens were chemically fi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774942/ https://www.ncbi.nlm.nih.gov/pubmed/31598314 http://dx.doi.org/10.1098/rsos.190915 |
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author | Burton, Hanna E. Cullinan, Rachael Jiang, Kyle Espino, Daniel M. |
author_facet | Burton, Hanna E. Cullinan, Rachael Jiang, Kyle Espino, Daniel M. |
author_sort | Burton, Hanna E. |
collection | PubMed |
description | The aim of this study was to investigate the multiscale surface roughness characteristics of coronary arteries, to aid in the development of novel biomaterials and bioinspired medical devices. Porcine left anterior descending coronary arteries were dissected ex vivo, and specimens were chemically fixed and dehydrated for testing. Surface roughness was calculated from three-dimensional reconstructed surface images obtained by optical, scanning electron and atomic force microscopy, ranging in magnification from 10× to 5500×. Circumferential surface roughness decreased with magnification, and microscopy type was found to influence surface roughness values. Longitudinal surface roughness was not affected by magnification or microscopy types within the parameters of this study. This study found that coronary arteries exhibit multiscale characteristics. It also highlights the importance of ensuring consistent microscopy parameters to provide comparable surface roughness values. |
format | Online Article Text |
id | pubmed-6774942 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Royal Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-67749422019-10-09 Multiscale three-dimensional surface reconstruction and surface roughness of porcine left anterior descending coronary arteries Burton, Hanna E. Cullinan, Rachael Jiang, Kyle Espino, Daniel M. R Soc Open Sci Engineering The aim of this study was to investigate the multiscale surface roughness characteristics of coronary arteries, to aid in the development of novel biomaterials and bioinspired medical devices. Porcine left anterior descending coronary arteries were dissected ex vivo, and specimens were chemically fixed and dehydrated for testing. Surface roughness was calculated from three-dimensional reconstructed surface images obtained by optical, scanning electron and atomic force microscopy, ranging in magnification from 10× to 5500×. Circumferential surface roughness decreased with magnification, and microscopy type was found to influence surface roughness values. Longitudinal surface roughness was not affected by magnification or microscopy types within the parameters of this study. This study found that coronary arteries exhibit multiscale characteristics. It also highlights the importance of ensuring consistent microscopy parameters to provide comparable surface roughness values. The Royal Society 2019-09-11 /pmc/articles/PMC6774942/ /pubmed/31598314 http://dx.doi.org/10.1098/rsos.190915 Text en © 2019 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Engineering Burton, Hanna E. Cullinan, Rachael Jiang, Kyle Espino, Daniel M. Multiscale three-dimensional surface reconstruction and surface roughness of porcine left anterior descending coronary arteries |
title | Multiscale three-dimensional surface reconstruction and surface roughness of porcine left anterior descending coronary arteries |
title_full | Multiscale three-dimensional surface reconstruction and surface roughness of porcine left anterior descending coronary arteries |
title_fullStr | Multiscale three-dimensional surface reconstruction and surface roughness of porcine left anterior descending coronary arteries |
title_full_unstemmed | Multiscale three-dimensional surface reconstruction and surface roughness of porcine left anterior descending coronary arteries |
title_short | Multiscale three-dimensional surface reconstruction and surface roughness of porcine left anterior descending coronary arteries |
title_sort | multiscale three-dimensional surface reconstruction and surface roughness of porcine left anterior descending coronary arteries |
topic | Engineering |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774942/ https://www.ncbi.nlm.nih.gov/pubmed/31598314 http://dx.doi.org/10.1098/rsos.190915 |
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