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Soluble fms‐like tyrosine kinase‐1‐enriched exosomes suppress the growth of small cell lung cancer by inhibiting endothelial cell migration

BACKGROUND: Previous studies have reported that soluble fms‐like tyrosine kinase‐1 (sFlt‐1) possesses anti‐tumor effects by inhibiting angiogenesis in many cancers. Exosomes can be engineered as delivery vehicles for transferring functional biomolecules, such as proteins, lipids, and nucleic acids (...

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Detalles Bibliográficos
Autores principales: Hao, Dexun, Li, Yanshuang, Zhao, Gaofeng, Zhang, Mingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775022/
https://www.ncbi.nlm.nih.gov/pubmed/31441580
http://dx.doi.org/10.1111/1759-7714.13175