Solution structure of the autophagy-related protein LC3C reveals a polyproline II motif on a mobile tether with phosphorylation site

(Macro-)autophagy is a compartmental degradation pathway conserved from yeast to mammals. The yeast protein Atg8 mediates membrane tethering/hemifusion and cargo recruitment and is essential for autophagy. The human MAP1LC3/GABARAP family proteins show high sequence identity with Atg8, but MAP1LC3C...

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Detalles Bibliográficos
Autores principales: Krichel, Carsten, Möckel, Christina, Schillinger, Oliver, Huesgen, Pitter F., Sticht, Heinrich, Strodel, Birgit, Weiergräber, Oliver H., Willbold, Dieter, Neudecker, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775092/
https://www.ncbi.nlm.nih.gov/pubmed/31578424
http://dx.doi.org/10.1038/s41598-019-48155-8

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